Case Reports

Integration and Vascular Ingrowth of a Collagen Meniscal Implant: A Case Report

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Francisco Guerra Pinto
Miguel Duarte Silva
Nuno Camelo Barbosa
Pedro Beja da Costa
Keywords:
Meniscal Implant, Collagen Scaffold, Biological Integration

Abstract

Meniscectomy is the most common surgery in orthopaedics. The absence of meniscal tissue might be related to irreversible damage to the articular cartilage. Meniscal replacement is a tissue-engineering technique for post-meniscectomy syndrome. Its success depends on the implant integration which was vastly proven in animal model studies. Histological evidence is hard to obtain in humans due to ethical issues. We report a clinical case in which a collagen scaffold meniscal implant was harvested six months after implantation due to mechanical failure. Histological analysis was performed revealing vascularisation not only of the peripheral attachment of the implant but also on the anterior horn. These morphologic findings demonstrate that this implant allows the colonisation by precursor cells and vessels, leading to the formation of a fully functional tissue. This present report is one of the few independent reports of scaffold biological integration in the literature.

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Corresponding Author

Miguel Duarte Silva, Department of Orthopaedics and Traumatology, Hospital de Cascais Dr. José de Almeida, Cascais, Portugal

Miguel Duarte Silva, Department of Orthopaedics and Traumatology,
Hospital de Cascais Dr. José de Almeida, Cascais, Lisboa, Portugal
E-mail: miguelduartesilva@gmail.com